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Does anyone know why does satiety initially drop after eating food and then increase 45 mins later?

I’m looking to understand a metabolic phenomenon that is observed by many folks. I haven’t found a good answer to this one yet. One is not so hungry, and then one eats something and then they feel a lot MORE hungry. And that can lead to overeating, even though original amount could have led to satiety 30-45 mins later! Why would the human body do this kind of stuff?

And maybe it depends on the food type and nutrient make up too (carbs/fat/protein/fiber and so on?).

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Answer

Grehlin is released by your stomach when empty and makes us feel hungry. Leptin is released by your fat cells and tells us we are full.

Leptin appears to have more impact on weight control for people.

Leptin is impacted by insulin and so does often increase more if you have a lot of carbs. The issue is that over time, our bodies receptors become resistant to the signal if levels are high too often. Similar to insulin resistance.

Good info on leptin here https://my.clevelandclinic.org/health/articles/22446-leptin

The most important adjustment to make is becoming more in tune with your stomach feeling full and not waiting for all this hormones to release. It took me a long time to become more intuitive with that link of “if my stomach feels like this now, I’ll feel satiated in 20-30 mins”

Also important here is that protein reduces grehlin (the “hunger” hormone) which is one of the reasons why eating a higher protein diet often leads to weight loss.

Think of it this way, fiber helps your stomach feel full more quickly, protein helps you not be as hungry, and fat slows digestion and works with hormones in your body to help to feel full more effectively.

Answer

Only happends on high carb diets. When I went carnivore(high fat, protein) im satisfied eating one meal a day. Plants/carbs are not nutrient dense enough. Thats why herbivores eat/chew almost all day long.

https://borgefagerli.no/wp-content/uploads/2015/09/blueberry-vs-kale-vs-beef-vs-liver-e1444813515994.jpg

Answer

I always thought that initial satiety was because of gastric stretch receptors. It just takes a little bit of time to register.

This explains why the initial food didn’t register. But would have later.

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