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High dose vs low dose vitamin D

Would it not be cheaper to take 2x pills of 5000IU vitamin D instead of 10x pills of 1000IU vitamin D since vit D is fat soluble? From a cost perspective, it seems like buying the 5000IU supplement is more of a bargain.

Edit: This is per week. Comparing taking 2x 5000 IU (One on Sat, One on Sun), compared to taking 1000 IU everyday. Also I mean this from a pure tablets per dollar ratio. If I can get 100 tablets of 5000 IU and 100 tablets of 1000 IU for the same price, then the 100 tablets of 1000 IU only lasts 100 days, where as the other lasts 50 weeks (assuming 1 on Sat, 1 on Sun).

FYI, paper that talks about upper limit: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7897606/

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Answer

Well first off, 5000iu is for people who are especially low in vitamin d. You wouldn’t want to be taking double doses of that

Also, it’s hard for me to say if that’s cheaper or not. Supplementation is just that - supplementing. It’s an aide. It’s not meant to be a main source of that nutrient. From a dietary standpoint, you would get your vitamin d from things like mushrooms, eggs, salmon. Sometimes dairy, or things like orange juice, are fortified with it. But you wouldn’t want to rely solely on a supplement

Fat soluble doesn’t mean it’s cheaper to supplement, it just means that your dietary fat helps absorb the nutrients, and is stored in fatty tissue. When you cook your food in olive oil, or eat things like avocados, that’s what’s helping you absorb certain nutrients

Also, in regards to fat solubility.., this is actually a good reason not to take two 5000Iu doses of vitamin d. It’s not like vitamin C, which is water soluble, that you’ll just pee out the excess when you’ve met your need. Vitamin D is very different,it’s stored in your fatty tissue and there is such a thing as too much. Matter of fact, a quick google search brings up this article. It seems like a hard condition to achieve, but it’s a good reason for why you wouldn’t want to take too high doses of vitamin d

Answer

I didn’t even know you can find 5k vitamin D pills. Is it D3?

Also, if it’s cheaper and you’re desperately low on vitamin D it might be worth it, but long term? I don’t think it’s necessary to get any more than 3k a day.

Some research I’ve seen suggests there’s no visible advantage for taking any more than that - unless you have a very specific reason for it.

If it’s just about general supplementing, you might want to stick with the 1k pills, IMO, unless ordered by a doctor.

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Just because the price per amount is cheaper doesn’t mean it’s neccesary lol. This only makes sense if u actually need to take 10k IU.

Otherwise you’re doing yourself a favor of ruining your health over a saving couple of dollars..Vitamin D is fat soluble just remember

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do you have a special reason for dosing so high?

i used to be big on vitamin D but now i’ve read this:

https://sciencebasedmedicine.org/should-you-take-vitamin-d-supplements/

“The VITAL trial was a large placebo-controlled study designed to address the cardiovascular and cancer benefits of omega-3 fatty acids and vitamin D for healthy adults. It found that vitamin D supplements don’t protect against developing cancer or cardiovascular disease, falls, cognitive decline, migraines, stroke, macular degeneration, or joint pain—nor do they reduce body weight or BMI.”

“In the light of the VITAL study and other recent research, the editorialists concluded:

Providers should stop screening for 25-hydroxyvitamin D levels or recommending vitamin D supplements, and people should stop taking vitamin D supplements to prevent major diseases or extend life.”

https://www.acc.org/latest-in-cardiology/clinical-trials/2018/11/08/22/42/vital

this is the trial in question, it seems well designed. it’s a big study. maybe 5 years isn’t long enough to detect much of a benefit? you could argue that 2000IU wasn’t sufficient but that is a reasonable dose imo.

does anyone have a rebuttal to this study?

Answer

I take Vitamin D3&K2 drops prescribed by my doctor. The daily dosage of 2 drops is 2500 IU of D3 (that’s 76,250 on average per month).

It’s combined with K2 as it plays an important role in the metabolism of D3. And the liquid drops are because I have starting leaky gut so it gets absorbed much better than pills. I had to switch my other multivitamin from pill form to powder form for that same reason.

Though liquid capsules will also work for that. And indeed, I was told to always combine it with breakfast or lunch because it’s fat soluble.

As far as I understood taking it daily in a lower dose is more effective than once a month in a high dose, because vitamins get processed relatively quickly by the body, so the positive effects will decrease over time if too much time is in between dosage.

If you’re looking to take 2 liquid capsules per week then I would recommend taking one in the weekend and one in the middle of the week to have a more even distribution.

Answer

A funny stroy: I had gotten diagnosed with avascular necrosis a year ago, and was told to take vit. D, which was 60,000 IU for around a month. And later I got my vit. D3 levels done. Guess what the levels were off the charts. But in retrospect I didn’t feel any of the symptoms. P.S. I know all the effects of hypervitaminosis, cause I’m in medical school.

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