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Long and complex article on fasting

So... the water got too deep for me pretty quickly, but there are a lot of interesting observations made in this article. I thought you folks might enjoy seeing it. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877980/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877980/)

Answer

The most interesting piece to me is that fasting downregulates mTOR and upregulates SIRT and autophagy. In short, these should lead to longer lifespan because your body does a much more thorough maintenance regiment triggered by the lack of caloric input. Plus the mental health improvements are interesting!